Tongkat Ali (Eurycoma longifolia): Pharmacology

Eurycoma longifolia is commonly known as Tongkat Ali. This herb is used in traditional medicine for a number of reasons including for fever and malaria. The fruits can also be used to cure dysentery, suggesting that it has an antimicrobial component to its fruit. The leaves are also used to cure itches, which may further suggest antifungal or antimicrobial effects. The bark can be used to treat worms of various kinds, and the tap roots appear to have blood pressure lowering effects. The roots can also be used as a general tonic and aphrodisiac and this may relate to the testosterone boosting effects of the plant. The plant contains a number of phytochemicals which may explain its wide ranging pharmacological activity including quassinoids, canthin-6-one alkaloids, β-carboline alkaloids, triterpene tirucallane type, squalene derivatives and biphenyl neolignan, eurycolactone, laurycolactone, and eurycomalactone, and bioactive steroids. Of these phytochemicals, quassinoids are a major component of the root.

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Rehman, S.U., Choe, K. and Yoo, H.H. 2016. Review on a traditional herbal medicine, Eurycoma longifolia Jack (Tongkat Ali): its traditional uses, chemistry, evidence-based pharmacology and toxicology. Molecules. 21(3): 331

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
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