Apigenin is a phytochemical that is a member of the flavonoid group of polyphenolic molecules. Within the flavonoids, apigenin belongs to the flavonol sub-group, and is therefore structurally related to quercetin and kaempferol. Evidence suggests that apigenin may have significant therapeutic effects, and this is something common to many flavonoids. In particular, apigenin may have cancer protective effects in humans and animals. The mechanism for this anti-cancer effect is not fully understood, but studies have observed that apigenin may be able to alter cell signal pathways, and by doing so may prevent the initiation and progression of cancer cell growth. The ability of apigenin to regulate cell signal pathways may relate to its antioxidant potential, or may be due to other mechanisms. As apigenin is not widespread in commonly eaten foods, its anticancer effects would necessitate the taking of supplements in order to obtain a consistently high therapeutic intake.
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