Category Archives: Adipose Tissue

Conjugated Linoleic Acid and Diabetes

Posted on July 8, 2013 by Robert Barrington

Conjugated linoleic acid (CLA) is a group of positional and geometric isomers of the essential fatty acid linoleic acid (LA, C18:2 (n-6)). Evidence suggests that conjugated linoleic acid may be beneficial in obesity because it causes weight loss. However, this … Continue reading →

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Cardiovascular Disease is a Condition of Inflammation

Posted on June 19, 2013 by Robert Barrington

Proponents of the cholesterol theory of cardiovascular disease believe that dietary cholesterol is the cause of atherosclerosis. Despite a large volume of evidence that contradicts this theory it is still popular amongst mainstream medicine. The most recent research in the … Continue reading →

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The Subcutaneous to Abdominal Fat Ratio

Posted on June 17, 2013 by Robert Barrington

Triglycerides are stored in two main repositories of white adipose tissue in humans. A subcutaneous store is present under the skin, and this constitutes the store of fat that it visible to the exterior. In addition, humans store fat around … Continue reading →

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Sleep Deprivation and Obesity

Posted on June 11, 2013 by Robert Barrington

The purpose of sleep in humans and animals is not fully understood. However, during sleep certain restorative processes are thought to occur, and hormonal cascades are hypothesised to be part of this process. Sleep is therefore necessary for normal physiological … Continue reading →

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Visceral Adiposity: Bad Fat, Bad News

Posted on May 5, 2013 by Robert Barrington

nsulin resistance in the likely cause of obesity. Dysfunction of the receptor signal pathway leads to an inability to oxidise fatty acids and glucose, and as a result ingested food is diverted away from skeletal muscle for oxidation and towards … Continue reading →

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Childhood Obesity: More Behavioural Factors

Posted on March 8, 2013 by Robert Barrington

It is becoming increasingly clear that obesity is not caused primarily by a simple energy imbalance. Serious metabolic dysfunction characterised by insulin resistance, that results in modification to normal physiological processes, has been identified in obese individuals and reported in … Continue reading →

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Fructose and Metabolic Syndrome; More Evidence

Posted on February 19, 2013 by Robert Barrington

The rise in the number of cases of obesity in the last 3 decades mirrors the 32% rise in dietary fructose between 1977 and 2004. High fructose corn syrup in particular has been implicated as a possible causative factor in … Continue reading →

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Does Leptin Regulate Appetite?

Posted on February 4, 2013 by Robert Barrington

Leptin acts as a feedback signal to the hypothalamus to decrease appetite and increase metabolic rate as adipose tissue accumulates. Administration of leptin to ob/ob leptin deficient mice causes dramatic reductions in body weight. From these results it was hoped … Continue reading →

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Benefits to Increased Meal Frequency

Posted on February 3, 2013 by Robert Barrington

Stabilisation of plasma glucose concentrations appears to be one of the pivotal requirements for weight loss. In clinical trials, increased protein and fibre intakes have both been shown to cause weight loss in overweight individuals, and this effect is likely … Continue reading →

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High Protein Diets Cause Adipocyte Remodelling

Posted on January 20, 2013 by Robert Barrington

The weight loss effects of high protein diets have been extensively studied in the scientific literature. Their satiating and thermogenic effects are well reported and is likely the mechanism by which they are able to cause weight loss in overweight … Continue reading →

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