Category Archives: Brain

Acetyl L-Carnitine and Fatigue

Posted on December 19, 2024 by Robert Barrington

L-carnitine plays a role in the oxidation of fatty acids and is therefore pivotal in energy production. Its acetyl derivative, acetyl L-carnitine, can also be used for this role, but may have other effects in the central nervous system as … Continue reading →

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Acetyl L-Carnitine and The Brain

Posted on December 17, 2024 by Robert Barrington

Acetyl L-carnitine is the principal acetyl ester of L-carnitine, a non proteinaceous amino acid that plays a role in the beta oxidation of fatty acids. Acetyl L-carnitine appears to be well tolerated by humans and does not show adverse effects … Continue reading →

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Synephrine and Raspberry Ketone: Why No Central Effects?

Posted on September 12, 2024 by Robert Barrington

Synephrine and raspberry ketone are structurally similar compounds found in Citrus Aurantium peel and Rubus Idaeus, respectively. Both compounds have a pharmacological profile that suggests that they cause lipolysis through activation of β3 adrenergic receptors. There is also likely some … Continue reading →

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Bergamot and Earl Grey Tea

Posted on September 4, 2024 by Robert Barrington

The bergamot orange (Citrus bergamia) is a citrus fruit that is used in aromatherapy as an anxiolytic and calmative agent. The rind of the orange is used to produce bergamot tea, which is black tea with added bergamot. Bergamot has … Continue reading →

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L-Theanine for Attention deficit hyperactivity Disorder 

Posted on August 26, 2024 by Robert Barrington

L-theanine is an amino acid found in tea. Evidence suggests that it can partially activate the N-methyl-D-aspartate (NMDA) glutamate receptor in humans and animals and that this causes a reduction in excitation in the brain along with a concomitant increase … Continue reading →

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Sudden Alcohol Withdrawal

Posted on August 7, 2024 by Robert Barrington

Addiction to alcohol can be a serious debilitating condition that leads to a slow deterioration in physical and mental health. Because of the damage that alcohol does to both the user and the people around them, individuals who abuse alcohol … Continue reading →

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Brain Regions Involved in Anxiety

Posted on August 6, 2024 by Robert Barrington

Anxiety has been hypothesised to be a survival mechanism by which threats are assessed and a more tentative and careful approach, following intense reflection, may confer advantages in dealing with situations. However, chronic anxiety, as can develop in humans and … Continue reading →

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Alcohol Addiction and Brain-Derived Neurotrophic Factor

Posted on August 5, 2024 by Robert Barrington

Brain derived neurotrophic factor (BDNF) is a peptide hormone under the regulation of the cyclic AMP response element binding (CREB) protein. Evidence suggests that BDNF is required for neuronal health, synaptic plasticity, and may play a role in memory and … Continue reading →

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The Acute Effect of Alcohol on Cognition

Posted on August 1, 2024 by Robert Barrington

Ingestion of alcohol is well evidenced to alter behaviour and change aspects of psychology. For example, impairment of cognition required for divided attention tasks occurs at relatively low intake of alcohol. This may be the reason that alcohol is particularly … Continue reading →

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L-Theanine and the Brain

Posted on March 21, 2024 by Robert Barrington

L-theanine (N-ethyl-L-glutamine) is a non-proteinaceous amino acid that is found in high amounts almost exclusively in tea (Camellia sinensis). In fact, L-theanine accounts for around 50 % of the amino acids in tea leaves. L-theanine is structurally similar to glutamic … Continue reading →

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