Category Archives: Cholecystokinin

Cholecystokinin: Anorectic Peptide

Posted on March 27, 2015 by Robert Barrington

Appetite regulation in humans is incredibly complex and involves complex feedback loops that pass from the gut to the central nervous system. These peptides interact with receptors in the hypothalamus, and this results in changes to subsequent food intake. The … Continue reading →

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Some Thoughts on Satiety

Posted on December 8, 2014 by Robert Barrington

The control of energy intake is important because it ensures that energy is available to allow work to be performed. The human body can store energy in a number of compartments, and regulation of these energy stores is pivotal in … Continue reading →

Posted in Bombesin, Cholecystokinin, Digestion and Absorption, Satiety, Weight Loss | Comments Off on Some Thoughts on Satiety

Protein and Lipids: Effects on Gut Function

Posted on August 3, 2014 by Robert Barrington

The dietary macronutrients are protein, carbohydrate and lipids. As well as providing substances required for metabolic regulation, these macronutrients have differing and interesting effects on gut function. In fact the basis of many weight loss diets is through manipulation of … Continue reading →

Posted in Cholecystokinin, Digestion and Absorption, Fatty Acids, Glucagon, Glucagon-like Peptide 1, Insulin, Protein, Triglycerides / Triacylglycerols, Weight Loss | Comments Off on Protein and Lipids: Effects on Gut Function

Protein: Gut Hormones and Satiety

Posted on May 9, 2014 by Robert Barrington

High protein diets show weight loss effect when compared to high fat or high carbohydrate diets. The reason for this is unknown, but protein has satiety inducing effects and this may contribute to its anti-obesogenic effects. The mechanisms by which … Continue reading →

Posted in Cholecystokinin, Ghrelin, Glucagon, Glucagon-like Peptide 1, Peptide YY, Protein, Satiety | Comments Off on Protein: Gut Hormones and Satiety

More On Medium Chain Triglyceride Digestion

Posted on April 21, 2014 by Robert Barrington

Medium chain fatty acids are defined as those with chain lengths of between 6 and 12 carbon atoms. Medium chain triglycerides are therefore three fatty acids of this length bonded through an ester bond to a glycerol molecule. Compared to … Continue reading →

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Bush Tucker Challenge

Posted on October 31, 2013 by Robert Barrington

A number of traditional diets have been studied regarding beneficial effects on postprandial glycaemia, including those of the Mediterranean, Pacific Island (Okinawan) and Australian bush regions. Evidence suggests that traditional diets are beneficial to the health because they contain few … Continue reading →

Posted in Cholecystokinin, Diabetes, Fibre, Glycaemic Index, Glycaemic load, Potato, Protein, Pulses / Legumes, Traditional Diets, Whole Grains | Tagged , | Comments Off on Bush Tucker Challenge

The Glycaemic Effect of Protein

Posted on October 10, 2013 by Robert Barrington

n elevated glycaemic response to food is increasingly being seen as a causative factor in the aetiology of the metabolic syndrome. This is problematic because the metabolic syndrome is associated with an increased risk of obesity, cardiovascular disease and type … Continue reading →

Posted in Cholecystokinin, Ghrelin, GIP, Glucagon-like Peptide 1, Glycaemic Index, Glycaemic load, Protein, Satiety | Tagged , | Comments Off on The Glycaemic Effect of Protein

Chewing and Energy Intake

Posted on September 4, 2012 by Robert Barrington

Traditionally, obesity has been thought of as a simple energy imbalance, whereby calorie intake becomes too great when compared to the amount of energy expended on metabolic processes and physical activity. However, within the last decade, a picture is emerging … Continue reading →

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Peptides that Regulate Feeding Behaviour: The anorectic Peptides

Posted on June 5, 2012 by Robert Barrington

Peptides that regulate appetite have been identified in the tissues of the gastrointestinal tract, pituitary, pancreas, hypothalamus and general neural tissues of mammals. These peptides tend to show paracrine, autocrine and endocrine functions that synergistically allows the regulation of energy … Continue reading →

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Nutrient Detection Regulates Energy Balance

Posted on May 18, 2012 by Robert Barrington

Mammals can maintain energy balance despite large fluctuations in physical activity and energy intakes because they have complex neuronal and hormonal systems that regulate appetite, satiety and metabolism. Short term appetite regulation is achieved by receptor mediated detection of food … Continue reading →

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