Category Archives: Enzymes

The High Fatkins Diet: Some Health Implications

Posted on July 2, 2014 by Robert Barrington

The ability of humans to adapt to dietary changes is well reported in the nutritional literature. For example, in a recent study published in the American Journal of Clinical Nutrition1, researchers assessed the ability of humans subjects to adapt to … Continue reading →

Posted in Cholesterol, Enzymes, Fat, Fibre, HDL, LDL, Trans Fatty Acids, Triglycerides / Triacylglycerols, VLDL | Comments Off on The High Fatkins Diet: Some Health Implications

Detoxification

Posted on May 2, 2012 by Robert Barrington

Detoxification of xenochemicals and toxins is vital for optimal health. There are a myriad of ways that this is achieved, but the primary mechanism involves biotransformation reactions performed by drug metabolising enzymes (DME). The detoxification process is split into an … Continue reading →

Posted in Detoxification, Enzymes | Comments Off on Detoxification

Flavonoid Enzyme Interactions

Posted on April 30, 2012 by Robert Barrington

Favonoids (here) are known to interact with a number of human detoxification enzymes, which greatly effects their bioactivity (here). These include both the phase I detoxification enzyme cytochrome P450 monooxygenase (CYP), and the phase II detoxification enzymes UDP-glucuronosyl transferase (UGT), … Continue reading →

Posted in Enzymes, Flavonoids, Phase II Detoxification | Comments Off on Flavonoid Enzyme Interactions

β-Amylase

Posted on March 10, 2012 by Robert Barrington

Amylases are a group of isoenzymes that are able to hydrolyse the glycosidic bonds in starch. The importance of starch as an energy source throughout life makes amylases important enzymes in both animals and plants. In humans and other mammals, … Continue reading →

Posted in Amylase, Enzymes | Comments Off on β-Amylase

Steroyl CoA Desaturase

Posted on February 3, 2012 by Robert Barrington

Lipids play an important role in cellular inflammation and research has identified a role for a number of dietary and endogenously produced fatty acids in the generation or inhibition of systemic inflammation. For example, the long chain polyunsaturated fatty acids … Continue reading →

Posted in Docosahexaenoic Acid, Eicosanoids, Eicosapentaenoic Acid, Enzymes, Fatty Acids, Inflammation, Insulin Resistance, Metabolic Syndrome, Monounsaturated Fatty Acids, Omega 3, Omega 6 | Comments Off on Steroyl CoA Desaturase

The Zinc Metalloproteins

Posted on April 13, 2011 by Robert Barrington

Research has demonstrated that humans need a large number of trace minerals to maintain health. Of these, zinc is the second most abundant trace mineral in the body after iron. In fact, zinc is present as a co-factor in more … Continue reading →

Posted in Enzymes, Zinc | Comments Off on The Zinc Metalloproteins

The Selenoproteins

Posted on April 11, 2011 by Robert Barrington

Many of the agricultural soils of Northern Europe and North America have low levels of selenium. Intensive agricultural practices and over farming have depleted the soil further of their selenium content, and a growing body of research is confirming that … Continue reading →

Posted in Enzymes, Selenium | Comments Off on The Selenoproteins