Category Archives: Fat

Substrate Oxidation and Macronutrient Intake

Humans do not require carbohydrates because they are not essential dietary components and withdrawal from the diet causes no obvious effects. However, they are a preferred source of fuel for the brain, and skeletal muscles must oxidise glucose during exercise … Continue reading

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More on High Fat Diets

Animal studies show that short-term changes to cardiac energy utilisation are reported with the administration of high fat diets. This partly results from increased availability of free fatty acids (FFA) as an energy source, and partly results from the ability … Continue reading

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Physiological Effects of Fat Droplet Size in The Duodenum

The macronutrients carbohydrate, protein and fat are known to regulate digestive physiology via the release or suppression of a number of specific gut hormones. The physiological effects of the hormones include alterations to satiety, gastric emptying and gut motility, changes … Continue reading

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Fibre and Adiponectin

Adiponectin is a cytokine released from adipose tissue and its circulating levels are inversely associated with the body fat mass of the individual. Adiponectin acts via the adenosine monophosphate-activated protein kinase (AMPK) secondary messenger systems to convert the  acetyl-Co A … Continue reading

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Is Food Addictive?

Evidence suggests that both fat and sugar are able to stimulate the dopamine reward pathways of the brain which acts to reinforce the behaviour of future consumption. Therefore fat and sugar have the potential for addiction in those that eat … Continue reading

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