Category Archives: Fatty Acids

More on Fructose and Serum Triglycerides

Posted on July 17, 2012 by Robert Barrington

Serum triglyceride concentrations are composed of two fractions. One fraction is composed of the endogenously produced very low density lipoproteins (VLDL) that are synthesised in the liver by the process of de novo lipogenesis. This process is active postprandially and … Continue reading →

Posted in de Novo Lipogenesis, Fatty Acids, Fructose, Triglycerides / Triacylglycerols, VLDL | Comments Off on More on Fructose and Serum Triglycerides

Plasma Fatty Acids of Alaskan Eskimos

Posted on July 5, 2012 by Robert Barrington

Native inhabitants of northern parts of Canada, Alaska and Greenland rely on marine sources for their protein and energy needs. These food sources tend to include both marine mammals and cold water fish that contain high levels of long-chain polyunsaturated … Continue reading →

Posted in Arachidonic Acid, Dihomo Gamma Linolenic Acid, Docosahexaenoic Acid, Eicosapentaenoic Acid, Essential Fatty Acids, Fatty Acids, Fish Oils, Gamma Linolenic Acid | Comments Off on Plasma Fatty Acids of Alaskan Eskimos

Vegetarian Diets and Inflammation

Posted on June 19, 2012 by Robert Barrington

High concentrations of arachidonic acid (AA, C20:4 (n-6)) in cell membranes are increasingly being associated with chronic disease and degeneration. Arachidonic acid is released from cell membranes by the action of phospholipase A2, and converted to pro-inflammatory eicosanoids, that can … Continue reading →

Posted in Alpha Linolenic Acid, Arachidonic Acid, Eicosapentaenoic Acid, Essential Fatty Acids, Fatty Acids, Inflammation, Linoleic Acid | Comments Off on Vegetarian Diets and Inflammation

More on High Fat Diets

Posted on May 24, 2012 by Robert Barrington

Animal studies show that short-term changes to cardiac energy utilisation are reported with the administration of high fat diets. This partly results from increased availability of free fatty acids (FFA) as an energy source, and partly results from the ability … Continue reading →

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Imbalances in Essential Fatty Acids

Posted on May 21, 2012 by Robert Barrington

The essential fatty acids (EFAs) linoleic acid (LA, C18:2 (n-6)) and α-linolenic acid (ALA, C18:3 (n-3)) can be metabolised to other more unsaturated, long-chain fatty acids by the insertion of additional double bonds during consecutive elongation and desaturation reactions. The … Continue reading →

Posted in Alpha Linolenic Acid, Arachidonic Acid, Dihomo Gamma Linolenic Acid, Docosahexaenoic Acid, Eicosapentaenoic Acid, Essential Fatty Acids, Fatty Acids, Fish, Fish Oils, Gamma Linolenic Acid, Inflammation | Comments Off on Imbalances in Essential Fatty Acids

Essential Fatty Acids in Early Development

Posted on April 24, 2012 by Robert Barrington

The two essential fatty acids (EFA), linoleic acid (LA, C18:2 (n-6)) and α-linolenic acid (ALA, C18:3 (n-3)), are required in the diet because humans are unable to synthesise them de novo. A series of elongation and desaturation reactions creates a … Continue reading →

Posted in Alpha Linolenic Acid, Dihomo Gamma Linolenic Acid, Docosahexaenoic Acid, Eicosanoids, Eicosapentaenoic Acid, Essential Fatty Acids, Fatty Acids, Fish Oils, Flax Oil, Gamma Linolenic Acid, Linoleic Acid, Pregnancy | Comments Off on Essential Fatty Acids in Early Development

More on Weight Loss

Posted on April 15, 2012 by Robert Barrington

The development of insulin resistance is a risk factor for the metabolic syndrome. Elevated levels of plasma fatty acids are associated with the development of insulin resistance, but the mechanisms are not fully understood. Fatty acids are taken up by … Continue reading →

Posted in Fatty Acids, Insulin Resistance, Metabolic Syndrome, Triglycerides / Triacylglycerols, Weight Loss | Comments Off on More on Weight Loss

Palmitoleic Acid

Posted on February 4, 2012 by Robert Barrington

Evidence suggests that ratios of cellular and circulating fatty acids in can have an effect on metabolic regulation. Palmitoleic acid (POA, C16:1 (n-7)) is an omega 7 fatty acid that is produced during de novo lipogenesis in humans. Palmitoleic acid … Continue reading →

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Steroyl CoA Desaturase

Posted on February 3, 2012 by Robert Barrington

Lipids play an important role in cellular inflammation and research has identified a role for a number of dietary and endogenously produced fatty acids in the generation or inhibition of systemic inflammation. For example, the long chain polyunsaturated fatty acids … Continue reading →

Posted in Docosahexaenoic Acid, Eicosanoids, Eicosapentaenoic Acid, Enzymes, Fatty Acids, Inflammation, Insulin Resistance, Metabolic Syndrome, Monounsaturated Fatty Acids, Omega 3, Omega 6 | Comments Off on Steroyl CoA Desaturase

Physiological Effects of Fat Droplet Size in The Duodenum

Posted on January 31, 2012 by Robert Barrington

The macronutrients carbohydrate, protein and fat are known to regulate digestive physiology via the release or suppression of a number of specific gut hormones. The physiological effects of the hormones include alterations to satiety, gastric emptying and gut motility, changes … Continue reading →

Posted in Fat, Fatty Acids, Triglycerides / Triacylglycerols | Comments Off on Physiological Effects of Fat Droplet Size in The Duodenum