Category Archives: Flavonoids

Cranberry Juice and Arterial Stiffness

Posted on August 18, 2012 by Robert Barrington

Berries are protective of cardiovascular disease, possibly because of the flavonoids that give them their blue and red colours. Although the mechanisms by which flavonoids provide vascular protection is unknown, epidemiological and clinical evidence continues to accumulate to show their … Continue reading →

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Coffee and Hypertension

Posted on August 13, 2012 by Robert Barrington

Hypertension is a known risk factor for cardiovascular and kidney disease and also increases all cause mortality. Many lifestyle factors have been identified that are known to affect blood pressure, including stress, smoking and exercise. The link between coffee consumption … Continue reading →

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Anthocyanins are Absorbed as Glycosides

Posted on May 8, 2012 by Robert Barrington

Flavonoid absorption is complex and not completely understood. However, it is known that on extensive metabolism occurs between the gastrointestinal tract and the plasma, such that the forms of flavonoid ingested are not reflective of the forms detected in plasma. … Continue reading →

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Green Tea Catechin Absorption

Posted on May 7, 2012 by Robert Barrington

Epidemiological evidence suggests that green tea may have beneficial health properties, particularly with regard to cancer and cardiovascular disease. This beneficial effect may be due to the high levels of antioxidant polyphenols present within the leaves of the Camellia sinensis … Continue reading →

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Absorption of Flavonols from Sea Buckthorn Berry

Posted on May 6, 2012 by Robert Barrington

Sea buckthorn berries are yellow fruits that contain high levels of vitamin C, tocopherols, carotenoids and flavonoids. Evidence suggests that sea buckthorn may possess antioxidant properties, and this may be responsible for its reported health effects against various parameters of … Continue reading →

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Absorption of Flavanones

Posted on May 5, 2012 by Robert Barrington

Naringenin (4’, 5, 7-trihydroxyflavanone) and hesperetin (3′, 5, 7-Trihydroxy-4′-methoxy flavanone) are flavanones that belong to the flavonoid group of phytochemicals. Flavanones possess antioxidant activity like all flavonoids, and in addition are phytoestrogens that may exert anti-oestrogenic effects. Naringenin has also … Continue reading →

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Flavonoid Structure and Antioxidant Activity

Posted on May 4, 2012 by Robert Barrington

Flavonoids are compounds that are produces by plants and are bioavailable in man. Evidence suggests that they have beneficial function on health, particularly against cancer and cardiovascular disease. One mechanism by which this may occur is through their antioxidant activity. … Continue reading →

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Flavonoid Enzyme Interactions

Posted on April 30, 2012 by Robert Barrington

Favonoids (here) are known to interact with a number of human detoxification enzymes, which greatly effects their bioactivity (here). These include both the phase I detoxification enzyme cytochrome P450 monooxygenase (CYP), and the phase II detoxification enzymes UDP-glucuronosyl transferase (UGT), … Continue reading →

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Anthocyanins

Posted on April 29, 2012 by Robert Barrington

Flavonoids represent a group of over 4000 compounds that contribute towards the colours in many plants. Consumption of fruits and vegetables is known from epidemiology to provide projection against certain diseases and flavonoids have been extensively researched in association with … Continue reading →

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Kaempferol Absorption

Posted on April 10, 2012 by Robert Barrington

Kaempferol is a flavonoid that belongs to the sub-group the flavonols. Like most flavonoids, kaempferol has been shown to be biologically active, and likely functions in vivo as an antioxidant on account of its polyphenolic structure. In addition, kaempferol may … Continue reading →

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