Category Archives: Homocysteine

Age and Homocysteine

Posted on January 21, 2013 by Robert Barrington

Despite mainstream medical ignorance of Kilmer McCully’s original homocysteine work four decades ago, homocysteine is now considered a risk factor for cardiovascular disease. Homocysteine is thought to increase the risk of cardiovascular disease via oxidative stress (although may also cause … Continue reading →

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Homocysteine and Endothelial Dysfunction

Posted on December 26, 2012 by Robert Barrington

Elevated plasma homocysteine is a risk factor for cardiovascular disease. Homocysteine is thought to increase the risk of cardiovascular disease because it is able to increase endothelial dysfunction in the arteries and cause athrogenesis. However, it is unknown if this … Continue reading →

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Homocysteine and Health

Posted on November 2, 2012 by Robert Barrington

Homocysteine is a metabolite of the amino acid methionine and elevated plasma levels are an independent risk factor for cardiovascular disease. Homocysteine levels become elevated due to low intakes of vitamin B6, B12 or folate, which are required as co-factors … Continue reading →

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Cobalamins and Homocysteine

Posted on October 7, 2012 by Robert Barrington

The cobalamins are a group of cobalt containing B vitamins (cyanocobalamin, methylcobalamin and adenosylcobalamin) that are collectively called vitamin B12. Vitamin B12 is required as a cofactor for methionine synthase, an enzyme that converts homocysteine to methionine using tetrahydrofolate (THF) … Continue reading →

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Choline, Betaine and Homocysteine

Posted on March 6, 2012 by Robert Barrington

Homocysteine is a metabolite of the essential amino acid methionine which can build up in cells and plasma if nutrition quality is low. High concentrations of plasma homocysteine are linked to an increased risk of cardiovascular disease and dementia, because … Continue reading →

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Sulfur Amino Acids and Immunity

Posted on January 29, 2012 by Robert Barrington

Methionine and cysteine are essential and conditionally essential amino acids, respectively. Both contain sulphur as part of their R group and are important nutritionally with regard immune function. Methionine can be converted in the body to cysteine via the intermediary … Continue reading →

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Determinants of Plasma Homocysteine

Posted on December 21, 2011 by Robert Barrington

Homocysteine is a sulphur containing amino acid formed from the metabolism of the essential amino acid methionine. High levels of homocysteine in the plasma have been identified as an independent risk factor for cardiovascular disease. Homocysteine metabolism depends on a … Continue reading →

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More on B Vitamins and Homocysteine Levels

Posted on October 21, 2011 by Robert Barrington

As discussed previously, elevated homocysteine levels are a risk factor for cardiovascular disease and possibly cancer, dementia and adverse pregnancy outcomes. Homocysteine is synthesised from methionine and under normal cellular conditions is quickly metabolised back to methionine via the enzyme … Continue reading →

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B Vitamins and Homocysteine Levels

Posted on October 20, 2011 by Robert Barrington

Elevated plasma homocysteine is a risk factor for cardiovascular disease, dementia, cancer and adverse pregnancy outcomes. Increases in homocysteine levels are associated with low intakes of vitamin B12, vitamin B6 and folic acid as well as a lack of exercise, … Continue reading →

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Homocysteine

Posted on August 10, 2011 by Robert Barrington

Homocysteine is a non-protein amino acid that is synthesised from the essential amino acid methionine. Excess homocysteine is toxic and has been identified as a risk factor for cardiovascular disease, dementia and neural tube defects during pregnancy. Homocysteinaemia is a … Continue reading →

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