Category Archives: Linoleic Acid

Diet Quality and Disease Risk

Growing evidence suggests that diet quality plays an important role in determining future disease risk. Lifestyle diseases associated with poor quality diet include cardiovascular disease, cancer, diabetes, metabolic syndrome and obesity. However, much of the research to date has focussed … Continue reading

Posted in Alpha Linolenic Acid, Arachidonic Acid, Calcium, Carbohydrate, Cardiovascular Disease, Carotenoids, Folate, Linoleic Acid, Mediterranean Diet, Trans Fatty Acids, Vegetables, Vitamin D, Vitamin K | Comments Off on Diet Quality and Disease Risk

More on Conjugated Linoleic Acid

Conjugated linoleic acid (CLA) is a mixture of isomers of the essential fatty acid linoleic acid (LA, C18:2 (n-6)), containing two conjugated double bonds. Diary products contain the CLA isomer cis-9, trans-11, but CLA is also produced industrially with the … Continue reading

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Energy Restriction and Longevity

Mammalian research suggests that long-term calorie reduction is associated with life extension. The telomere is the repetitive nucleotide sequence at the end of a chromatid that protects the chromosomes from fusion during replication. As mammals age, this telomere shortens, with … Continue reading

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Lipoprotein Fatty Acid Composition

Very low density lipoproteins (VLDL) represent the lipoprotein fraction measured as plasma triglycerides. Following absorption to the plasma within chylomicrons, triglycerides are passed to the liver where they are arranged into VLDL particles. The composition of the VLDL particles therefore … Continue reading

Posted in Arachidonic Acid, LDL, Linoleic Acid, Monounsaturated Fatty Acids, Olive Oil, Olives, Oxidative Stress, VLDL | Comments Off on Lipoprotein Fatty Acid Composition

Are Docosahexanoic Acid Intakes Too Low?

Long chain polyunsaturated acids from fish are required for the correct development of the brain and retinal in infants and children. In particular, docosahexanoic acid (DHA, C22:6 (n-3)) has been researched with respect to central nervous system growth in early … Continue reading

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Systemic Inflammation and Diet

Recent evidence suggests that obesity is associated with low level chronic inflammation. This may deplete antioxidant defences through the generation of systemic oxidative stress, and result in the formation of diseases such as diabetes, cardiovascular disease and cancer. An inverse … Continue reading

Posted in Alpha Linolenic Acid, Antioxidant, Arachidonic Acid, Eicosapentaenoic Acid, Essential Fatty Acids, Inflammation, Linoleic Acid, Obesity, Oxidative Stress, Rosavins / Salidrosides | Comments Off on Systemic Inflammation and Diet

Linoleic Acid and Lipoprotein Oxidation

Linoleic acid (LA, C18:2 (n-6)) is an essential fatty acid that is required in human nutrition for the production of eicosanoid hormones that regulate inflammation, immunity and other important cellular functions. Linoleic acid deficiency is rare because the typical Western … Continue reading

Posted in Cardiovascular Disease, Essential Fatty Acids, HDL, Heart Disease, LDL, Linoleic Acid, VLDL | Comments Off on Linoleic Acid and Lipoprotein Oxidation

More on EFA Interactions

The long chain polyunsaturated fatty acids (PUFA) eicosapentanoic acid (EPA, C20:5 (n-3)) and docosahexanoic acid (DHA, C22:6 (n-3)) accumulate in cell membranes where they provide protection against cardiovascular disease. This is because they are converted to eicosanoid hormones that regulate … Continue reading

Posted in Alpha Linolenic Acid, Arachidonic Acid, Cardiovascular Disease, Dihomo Gamma Linolenic Acid, Docosahexaenoic Acid, Eicosanoids, Eicosapentaenoic Acid, Essential Fatty Acids, Linoleic Acid | Comments Off on More on EFA Interactions

Vegetarian Diets and Inflammation

High concentrations of arachidonic acid (AA, C20:4 (n-6)) in cell membranes are increasingly being associated with chronic disease and degeneration. Arachidonic acid is released from cell membranes by the action of phospholipase A2, and converted to pro-inflammatory eicosanoids, that can … Continue reading

Posted in Alpha Linolenic Acid, Arachidonic Acid, Eicosapentaenoic Acid, Essential Fatty Acids, Fatty Acids, Inflammation, Linoleic Acid | Comments Off on Vegetarian Diets and Inflammation

Essential Fatty Acids and Childhood Adiposity

The essential fatty acids α-linolenic acid (ALA, C18:3 (n-3)) and linoleic acid (LA, C18:2 (n-6)) are required for normal human metabolism. Chronic sub-clinical deficiencies of these fatty acids are increasingly being linked to major diseases such as cardiovascular disease and … Continue reading

Posted in Alpha Linolenic Acid, Docosahexaenoic Acid, Eicosapentaenoic Acid, Essential Fatty Acids, Linoleic Acid, Pregnancy | Comments Off on Essential Fatty Acids and Childhood Adiposity