Category Archives: Metabolic Syndrome

Insulin Resistance and Nonalcoholic Fatty Liver

Nonalcoholic fatty liver disease (NAFLD) is a recently identified phenomenon, whereby the liver becomes diseased through a mechanisms that is independent of alcohol consumption. Nonalcoholic fatty liver disease is almost identical pathologically to alcoholic fatty liver disease, but while the … Continue reading

Posted in Fatty Acids, Fructose, Insulin Resistance, Metabolic Syndrome, Non-alcoholic Fatty Liver Disease, Obesity, Triglycerides / Triacylglycerols | Comments Off on Insulin Resistance and Nonalcoholic Fatty Liver

Insulin Resistance and Cardiovascular Disease

The lipid theory of cardiovascular disease states that atherosclerosis, lesions and inelasticity in artery walls, was caused by dietary lipids including saturated fat and cholesterol. However, the scientific evidence does not support this contention and the lipid theory of cardiovascular … Continue reading

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Are Legumes Protective Of Cardiovascular Disease?

Leguminous plants include the beans, lentils and peas. The leguminous plants produce seeds which are called pulses. Humans eat legumes including pulses and these provide high levels of many nutrients and are excellent sources of protein, starch and phytonutrients. Evidence … Continue reading

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Metabolic Syndrome: The Common Link Between Diabetes and Cardiovascular Disease?

The metabolic syndrome is a cluster of metabolic dysfunctions that centre on the development of insulin resistance. Insulin resistance, is a condition that occurs when the hormone insulin no longer is able to elicit cellular effects efficiently. As a result … Continue reading

Posted in Adipose Tissue, Cardiovascular Disease, Diabetes, Endothelial Dysfunction, Insulin Resistance, Metabolic Syndrome, Nitric Oxide | Comments Off on Metabolic Syndrome: The Common Link Between Diabetes and Cardiovascular Disease?

Is Oxidative Stress The Main Driver of Insulin Resistance?

Obesity, cardiovascular disease and type 2 diabetes are all aetiologically linked through the metabolic syndrome. The observation that all three diseases are associated with oxidative stress, has lead some to speculate that oxidative stress is the causative factor in metabolic … Continue reading

Posted in Fatty Acids, Free Radicals, Fructose, Insulin Resistance, Metabolic Syndrome, Oxidative Stress, Sugar | Comments Off on Is Oxidative Stress The Main Driver of Insulin Resistance?

Do You have Metabolic Syndrome?

The metabolic syndrome is a cluster of metabolic disorders that are likely caused by the insulin resistance that characterises the condition. These metabolic disorders include, but are not limited to, changes to plasma lipoproteins, raised levels of fasting blood glucose, … Continue reading

Posted in Abdominal Obesity, Insulin Resistance, Metabolic Syndrome, Non-alcoholic Fatty Liver Disease | Comments Off on Do You have Metabolic Syndrome?

Vitamin D and Blood Glucose Homeostasis

Vitamin D is a steroid hormone, classified as a vitamin. As well as dietary sources of vitamin D, humans can synthesise vitamin D in the skin through the action of ultraviolet light acting on cholesterol. The biologically accepted marker for … Continue reading

Posted in 1,25-dihydroxyvitamin D / Calcitriol, 25-hydroxyvitamin D, Abdominal Obesity, Insulin Resistance, Metabolic Syndrome, Vitamin D | Comments Off on Vitamin D and Blood Glucose Homeostasis

Metabolic Syndrome in Normal Weight Individuals

The metabolic syndrome is a cluster of metabolic disorders that develop due to an underlying insulin resistant state. As insulin sensitivity declines, blood sugar levels rise and insulin production increases in response to ingested carbohydrate ingestion. Such a hyperglycaemic hyperinsulinaemic … Continue reading

Posted in Abdominal Obesity, Adipose Tissue, Glycaemia, Insulin Resistance, Metabolic Syndrome, Obesity, Western Diet | Comments Off on Metabolic Syndrome in Normal Weight Individuals

Choline: The Old New Supplement

Choline has been around as a dietary supplement for a long time. Its use as a treatment for the accumulation of fat in the liver is well recorded in the nutritional literature from both animal and human studies. In the … Continue reading

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Antioxidant Supplements: More Evidence They Work

Oxidative stress is associated with the aetiology of many of the Western lifestyle diseases such as metabolic syndrome, cardiovascular disease, obesity and type 2 diabetes. Although an association does not prove a cause and effect, studies with animals and humans … Continue reading

Posted in Antioxidant, Diabetes, Fructose, Inflammation, Insulin Resistance, Metabolic Syndrome, Obesity, Selenium, Tocopherols, Tocotrienols, Vitamin C, Vitamin E, Weight Loss | Comments Off on Antioxidant Supplements: More Evidence They Work