Category Archives: Phase II Detoxification

Brussels Sprouts as a Source of Glucosinolates

Posted on December 28, 2014 by Robert Barrington
Posted in Brassica, Broccoli, Cancer, Cauliflower, Cruciferous Vegetables, Glucosinolates, Isothiocyanates, Phase I Detoxification, Phase II Detoxification | Comments Off on Brussels Sprouts as a Source of Glucosinolates

Red Wine: Gut Bacteria Modulator

Posted on June 8, 2013 by Robert Barrington

Red wine is difficult to study scientifically because it is a highly complex mixture of chemical compounds, that changes composition over time and which shows variety between different wine types. However, generally research investigating the effects of red wine have … Continue reading →

Posted in Blood Pressure, Cardiovascular Disease, Phase II Detoxification, Polyphenols, Red Wine, Resveratrol, Wine | Tagged , , , | Comments Off on Red Wine: Gut Bacteria Modulator

Glutathione S-Transferase Genotype and Vitamin C Plasma Levels

Posted on September 15, 2012 by Robert Barrington

Glutathione S-transferases are a family of phase 2 detoxification enzymes that play an important role in the metabolism of endogenous and exogenous compounds. Compounds that can be metabolised by the GST enzyme family include carcinogens, environmental toxins and reactive oxygen … Continue reading →

Posted in Cholesterol, Detoxification, Epigenetics, Glutathione, Iron, LDL, Phase II Detoxification, Vitamin C | Comments Off on Glutathione S-Transferase Genotype and Vitamin C Plasma Levels

Flavonoid Enzyme Interactions

Posted on April 30, 2012 by Robert Barrington

Favonoids (here) are known to interact with a number of human detoxification enzymes, which greatly effects their bioactivity (here). These include both the phase I detoxification enzyme cytochrome P450 monooxygenase (CYP), and the phase II detoxification enzymes UDP-glucuronosyl transferase (UGT), … Continue reading →

Posted in Enzymes, Flavonoids, Phase II Detoxification | Comments Off on Flavonoid Enzyme Interactions