Category Archives: S-adenosylmethionine

S-Adenosylmethionine (SAMe) For Depression

Posted on March 24, 2021 by Robert Barrington

Methylation is an important metabolic process. Methylation is used by cells as a way to activate or deactivate molecules through the transfer of methyl groups. As methyl groups are made up of one carbon molecule, this cyclical metabolic process is … Continue reading →

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S-Adenosylmethionine and Mood

Posted on December 14, 2020 by Robert Barrington

S-adenosylmethionine (SAMe) is a naturally occurring compound found in cells that is required for a number of metabolic pathways. In these pathways SAMe is often used to transfer a methyl chemical group and in this way the compound is involved … Continue reading →

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SAM: Associated With Adiposity

Posted on December 26, 2014 by Robert Barrington

S-adenosylmethionine (SAM) is an intermediate high energy compound of the methionine to homocysteine pathway. Methionine is an essential amino acid in human nutrition, and is derived mainly from animal protein in the diet of Westerners. Methionine is converted to SAM, … Continue reading →

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Make Sure Your Mother Gets Her B12 (Before You Are Born)

Posted on November 11, 2014 by Robert Barrington

Choline is an important component of phospholipids, functions in lipid metabolism and is also able to form the neurotransmitter acetylcholine. Choline can be derived from the diet, but is also synthesised endogenously. The synthesis of choline requires methylation and this … Continue reading →

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Folic Acid Supplementation in Intermediate Homocysteinaemia

Posted on February 15, 2013 by Robert Barrington

A high plasma concentration of homocysteine is a risk factor for cardiovascular disease, and studies have shown that 0.5 to 5 mg of folic acid as a dietary supplement can lower homocysteine by 25%. Cellular S-adenosylmethionine (SAMe) is an intermediate … Continue reading →

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Creatine and Fatty Liver in Rats

Posted on October 13, 2012 by Robert Barrington

Animal studies have limited relevance to human nutrition, but sometimes a study appears that is of sufficient interest to warrant discussion. One such paper published in the Journal of Nutrition is 20111, involved creatine supplementation to rats with non-alcoholic fatty … Continue reading →

Posted in Creatine, Non-alcoholic Fatty Liver Disease, Oxidative Stress, S-adenosylmethionine | Comments Off on Creatine and Fatty Liver in Rats