Category Archives: Selenium

Selenium Toxicity

Posted on March 21, 2012 by Robert Barrington

The toxicity of most trace minerals is well understood and mechanisms are well documented in academic papers. Because selenium can accumulate in body proteins there is the potential for toxicity and this has been extensively studied in animal models. The … Continue reading →

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A little More on Selenium

Posted on March 20, 2012 by Robert Barrington

Methionine is an essential amino acid and as a result humans are unable to synthesise selenomethionine. However, Selenomethionine is synthesised in plants via bonding of inorganic forms of selenium to the essential amino acid methionine (particularly in brassica and allium … Continue reading →

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Optimal Selenium Intake

Posted on September 13, 2011 by Robert Barrington

Selenium is a trace mineral that is incorporated into selenoproteins, the most well known of which is the antioxidant enzyme glutathione peroxidase. However, selenoprotein P is increasingly being seen as a reliable marker for selenium status. Deficiency of selenium is … Continue reading →

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Whole Grains Lower C Reactive Protein

Posted on September 9, 2011 by Robert Barrington

Inflammation is increasingly being linked with disease. C-reactive protein (CRP) is a known marker of chronic inflammation in humans and has been linked to increased risk of cardiovascular disease and poorer outcomes for those who have suffered a myocardial infarction. … Continue reading →

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More on Selenium Absorption

Posted on August 11, 2011 by Robert Barrington

Selenium is an important trace mineral that is incorporated into a number of selenoproteins. Important selenoproteins include glutathione peroxidase, thioredoxin reductase, iodothyronine deiodinase and selenoprotein-P. Selenium is of interest because evidence suggests that a deficiency of selenium can increase the … Continue reading →

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Selenium Bioavailability

Posted on July 20, 2011 by Robert Barrington

Selenium is an important trace mineral incorporated into a number of important selenoproteins. These selenoproteins have important biological functions and include glutathione peroxidase, thioredoxin reductase, iodothyronine deiodinase and selenoprotein-P.  In order for selenium compounds to be of use to the … Continue reading →

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Inverse Association between Selenium and Cancer?

Posted on July 16, 2011 by Robert Barrington

Research indicates that low plasma and cellular levels of selenium may increase the risk of developing many types of cancer (here). Research also indicates that supplementing with 200 µg per day of selenium as yeast, may reduce the overall cancer … Continue reading →

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More on Selenium

Posted on May 25, 2011 by Robert Barrington

Selenium is an important trace mineral in humans, which is incorporated into a number of selenoproteins such as glutathione peroxidase, iodothyronine deiodinase and thioredoxin reductase (here). It is known that supplementing with 200 µg of selenium a day reduces the … Continue reading →

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Selenium and Immune Function

Posted on April 30, 2011 by Robert Barrington

Selenium is an essential trace mineral, needed by the body for the production of a number of selenoproteins. It is becoming clear that dietary intakes of selenium in the general population of Northern Europe, Russia, New Zealand, North America and … Continue reading →

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Selenium Supplements

Posted on April 28, 2011 by Robert Barrington

Selenium is an essential trace mineral that is incorporated into a number of important selenoproteins in the body, such as selenoprotein P, glutathione peroxidase, iodothyronine deiodinase, thioredoxin reductase and selenoprotein W. A full clinical deficiency of selenium is rare and … Continue reading →

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