Category Archives: Vitamin B

Homocysteine And Colorectal Cancer

Posted on April 13, 2014 by Robert Barrington

Homocysteine is a product of methionine metabolism in humans. Under conditions of adequate nutrition, this homocysteine is rapidly converted back to methionine or to cysteine through a number of pathways. For this conversion to take place, optimal intakes of folic … Continue reading →

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Pyridoxal Phosphate Inhibited By Theophylline

Posted on January 29, 2014 by Robert Barrington

Pyridoxal phosphate is the activated version of pyridoxal, part of the vitamin B6 group of vitamins (here). The vitamin functions in a large number of reactions as a cofactor for amino acid metabolism. Low plasma levels of pyridoxal phosphate are … Continue reading →

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Vitamin B6 Supplements in Pregnancy

Posted on January 20, 2014 by Robert Barrington

  We are told by medical experts that vitamin supplements are not necessary and we acquire all the nutrients we need from food. In fact the more cynical amongst us may claim that there is even the possibility of a … Continue reading →

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Vitamin B6: Ethanol Inhibits Absorption

Posted on December 21, 2013 by Robert Barrington

Pyridoxine (vitamin B6: here) is a group of related chemicals that play an important role as coenzymes in energy metabolism in humans. Dietary pyridoxine is absorbed to enterocytes of the gut and then phosphorylated to pyridoxal 5’-phosphate, the active coenzyme … Continue reading →

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Vitamin B Insufficiencies In The Elderly

Posted on December 15, 2013 by Robert Barrington

It is often assumed that an ageing person has an inevitable slide into functional disability. Proponents of such an idea can readily find data from the literature showing reductions in muscle mass, deteriorations in cognitive function and increases in blood … Continue reading →

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Folic Acid: More Deficiencies

Posted on November 29, 2013 by Robert Barrington

Folic acid (here) is one of the B complex of vitamins, found in foods such as green leafy vegetables. Recent research based on work by Kilmer McCully in the 1960’s (here) has uncovered a role for folic acid in the … Continue reading →

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Vitamin B6 Supplements: How Much?

Posted on November 24, 2013 by Robert Barrington

Vitamin B6 (here) is a group of vitamers made up of pyridoxine, pyridoxal and pyridoxamine, which are required in human metabolism for amino acid metabolism. Food sources of vitamin B6 include meat and whole grain foods, but supplements containing the … Continue reading →

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The B6 Essential Fatty Acid Connection

Posted on October 15, 2013 by Robert Barrington

eficiencies of vitamin B6 are known to increase the risk of developing cardiovascular disease. The mechanisms for this was first described by Kilmer McCully in his seminal paper in the 1960’s, in which he investigated cardiovascular disease risk in young … Continue reading →

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Total Body Stores of Vitamin B6

Posted on September 28, 2013 by Robert Barrington

The concentration of vitamins in the diet is significantly larger than the total body pool for most vitamins. This is particularly true for the water soluble vitamins that are not stored in body tissues to any great extent. The reason … Continue reading →

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Low Fat Diets: More Confounding Variables

Posted on September 9, 2013 by Robert Barrington

roponents of the cholesterol theory of cardiovascular disease believe that dietary cholesterol and saturated fatty acids are the cause of cardiovascular disease. The mechanism for this we are told is based on the erroneous belief that dietary cholesterol and saturated … Continue reading →

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