Category Archives: VLDL

Malonyl-CoA: Pivotal In Insulin Resistance?

Malonyl-CoA is an intermediate in the de novo synthesis of fatty acids. Stimulation of the de novo lipogenesis pathway therefore increases the production of malonyl-CoA. Malonyl-CoA is an important intermediate in this pathway because it allosterically inhibits a number of … Continue reading

Posted in de Novo Lipogenesis, Fatty Acids, Insulin Resistance, LDL, Triglycerides / Triacylglycerols, VLDL | Comments Off on Malonyl-CoA: Pivotal In Insulin Resistance?

Fish Oils Improve Insulin Resistance

Fish oils are the fats obtained from fish such as mackerel, tuna, salmon and trout. They are highly polyunsaturated fatty acids that are composed primarily of eicosapentaenoic (EPA, C20:5 (n-3)) and docosahexaenoic acid (DHA, C22:6 (n-3) which belong to the … Continue reading

Posted in Docosahexaenoic Acid, Eicosanoids, Eicosapentaenoic Acid, Fish, Fish Oils, Inflammation, Insulin Resistance, Triglycerides / Triacylglycerols, VLDL | Comments Off on Fish Oils Improve Insulin Resistance

Low Carbohydrate Diets Increase Lipoprotein Particle Size

Raised levels of certain lipoproteins are associated with cardiovascular disease. However, it should be emphasised here that while raised levels of these lipoproteins are associated with cardiovascular disease, the cause and effect is not proven. The traditional view was that … Continue reading

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Low Carbohydrate Diets Increase LDL Particle Size

Posted in Carbohydrate, Cardiovascular Disease, Cholesterol, HDL, LDL, VLDL, Zone Diet | Comments Off on Low Carbohydrate Diets Increase LDL Particle Size

Low Carbohydrate Diets Improve LDL to HDL Ratios

Low fat diets have been shown to decrease levels of low density lipoprotein (LDL) cholesterol, whilst low carbohydrates have been shown to increase LDL cholesterol. Elevated levels of LDL have traditionally been seens as a risk factor for cardiovascular disease … Continue reading

Posted in Carbohydrate, Cardiovascular Disease, Cholesterol, HDL, LDL, Triglycerides / Triacylglycerols, VLDL | Comments Off on Low Carbohydrate Diets Improve LDL to HDL Ratios

Low Carbohydrate Diets Lower Fasting Plasma Triglycerides

Low carbohydrates diets appear to be effective in treating obesity. This may relate to the ability of such diets to improve insulin sensitivity. If this hypothesis is correct, it would be expected that such diets would be effective because they … Continue reading

Posted in Carbohydrate, de Novo Lipogenesis, Fructose, Triglycerides / Triacylglycerols, VLDL, Weight Loss | Comments Off on Low Carbohydrate Diets Lower Fasting Plasma Triglycerides

Rats, Fructose and Insulin Resistance

Posted in Blood Pressure, Fructose, Insulin Resistance, Triglycerides / Triacylglycerols, VLDL | Comments Off on Rats, Fructose and Insulin Resistance

Want to Lower Cholesterol? Try A Fast

High levels of plasma cholesterol are not the cause of cardiovascular disease. In fact, the available evidence suggests that the relationship between plasma cholesterol and cardiovascular disease is not causal, but is controlled by another variable. This variable is likely … Continue reading

Posted in Cholesterol, Fasting, Fruit, Fruit Juice, HDL, LDL, Tea, VLDL | Comments Off on Want to Lower Cholesterol? Try A Fast

Sucrose: A Tail of Two Sugars

Sucrose is the chemical name for table sugar. It is the white crystalline powder that most people put in their tea or coffee. Sucrose is chemically a disaccharide sugar, which means that it is composed of two monosaccharides joined together … Continue reading

Posted in Cholesterol, Fructose, Glucose, LDL, Sucrose, Sugar, VLDL, Western Diet | Comments Off on Sucrose: A Tail of Two Sugars

Guar Gum: Statin Beaters

Elevated levels of blood lipoproteins are caused by poor quality diets. Low quality foods containing refined cereal grains and refined crystalline fructose induced insulin resistance and this raises plasma levels of fasting insulin. Insulin is the primary anabolic hormone, and … Continue reading

Posted in Cholesterol, Fibre, Insulin, Insulin Resistance, LDL, Pulses / Legumes, VLDL | Comments Off on Guar Gum: Statin Beaters