Cellular Effects of Raspberry Ketones

Raspberry ketones have been evidenced in animal studies to protect from the damaging effects of overconsumption of energy. In addition, studies in animals show that raspberry ketones can also reduce body fat in overweight animals. In human studies, similar effects are seen with raspberry ketones, and these include the ability to cause weight loss and protect from fatty liver and insulin resistance. Because of these effects, it is interesting to speculate on the possible cellular mechanisms by which these effects can occur. A number of cellular studies have attempted to elucidate this aspect of the pharmacology of raspberry ketones and have published evidence that supports a weight loss effect. For example, in one study the researchers observed an increase in lipolysis and an increase in fatty acid oxidation in cell culture models. In addition, raspberry ketones increase the expression of adiponectin, and adipocytokine, which has been shown to have anti obesity effects in humans and animals. The study authors concluded that raspberry ketones may be a potentially useful supplement in the treatment of obesity and could be used therapeutically to increase fat oxidation and protect from weight gain. 

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Park, K.S., 2010. Raspberry ketone increases both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes. Planta medica. 76(15): 1654-1658

About Robert Barrington

Robert Barrington is a writer, nutritionist, lecturer and philosopher.
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