Raspberry ketones are aromatic compounds present in the fruit of the red raspberry plant (Rubus idaeus), Raspberry ketones have a structure similar to that of capsaicin, a compound found in chillies. Pharmacological studies show that ingestion of raspberry ketones may have weight loss effects because the raspberry ketones are able to activate the nervous system which may stimulate fatty acid oxidation. This is a property previously shown for capsaicin. Dermal application of raspberry ketones may have a similar effect by activating sensory neurones. This process is thought to lead to increased skin elasticity and the promotion of hair growth, through the ability of the raspberry ketones to stimulate the synthesis and release of insulin-like growth factor (IGF) in the skin cells. This effect has been demonstrated in humans and mice, and with regard to the former, application of raspberry ketones has been shown to cause hair growth in cases of alopecia when applied to the face and scalp at a concentration of 0.01 % solution after 5 months. This application also increased cheek elasticity after 2 weeks.
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