Rhizoma drynariae is the dry root tuber of the perennial fern Drynaria fortunei. Rhizoma drynariae is found in the Guangdong, Guangxi and Sichuan provinces in China. Evidence suggests that Rhizoma Drynariae may have significant medical effects, particularly on account of its ability to decrease oxidative stress. This suggests that the plant tissue is rich in antioxidants. One group of phytochemicals within Rhizoma Drynariae that may be useful in the treatment of osteoporosis are the flavonoids. Studies suggest that treatment of patients with osteoporosis with a combination of Rhizoma Drynariae and calcium, may significantly reduce the production of reactive oxygen species associated with osteoporosis. This can be measured clinically by increases in levels of certain antioxidant enzyme systems such as glutathione peroxidase and superoxide dismutase. The main findings of the study however were that associated with these changes, there was a reduced loss of bone tissue.
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