Coenzyme Q10 is required for the correct production of energy in mitochondria. In this role, it is vital to the production of energy in all eukaryotic cells. Supplemental coenzyme Q10 may have antioxidant and energy production roles, and this may be particularly apparent in the elderly because coenzyme Q10 synthesis declines with age. Coenzyme Q10 has a number of clinical applications relating to the treatment of specific diseases. For example, coenzyme Q10 is useful in the treatment of cardiovascular disease. Coenzyme Q10 improves endothelial function and as endothelial function is implicated in the development of cardiovascular disease, this explains the cardioprotective role of coenzyme Q10. In cardiac patients coenzyme Q10 levels in the blood can be used to predict mortality. A number of mitochondrial diseases also respond to coenzyme Q10 supplements and there may be some clinical use for coenzyme Q10 in ameliorating some of the symptoms of dementia and reducing the severity of headaches.
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